For research use only. Not for human consumption.
HCG (Human Chorionic Gonadotropin) | 5000iu
For topical application only.
HCG is a complex glycoprotein hormone naturally produced by the syncytiotrophoblast cells of the placenta. Structurally, it is a heterodimer consisting of an alpha subunit—identical to those in LH, FSH, and TSH—and a unique beta subunit, which determines its specific biological activity. In laboratory research, HCG is primarily utilized as a potent Luteinizing Hormone (LH) mimetic, binding to and activating the LH/choriogonadotropin receptor (LHCGR).
Technical Specifications
| Feature | Details |
|---|---|
| Purity | 99% (Validated by HPLC/MS) |
| Concentration | 5000iu per vial |
| Molecular Weight | ~36,700 g/mol |
| Form | White lyophilized powder |
| Subunits | alpha (92 amino acids) / beta (145 amino acids) |
| Storage | 2–8°C, protected from light |
Key Product Features
- LH Mimicry: Researched for stimulating Leydig cells in testes or inducing ovulation in ovarian research models.
- COA Verified: Each batch undergoes rigorous testing to ensure 5000iu potency and ≥99% purity for high-precision endocrinology assays.
- Structural Integrity: Lyophilized using advanced methods to preserve delicate carbohydrate chains essential for receptor binding and biological half-life.
The Science of HCG: Mechanism of Action
Research focuses on HCG’s role in the Hypothalamic-Pituitary-Gonadal (HPG) axis:
- Gonadal Stimulation: Binds LHCGR to trigger conversion of cholesterol to pregnenolone, the precursor to all steroid hormones.
- Steroidogenesis: Investigated for maintaining intratesticular testosterone in male models even under suppressed pituitary function.
- Metabolic & Differentiation Studies: Explored for effects on non-gonadal tissues, including cell differentiation and immune modulation.
Research FAQ
How should HCG be stored?
- Lyophilized powder: 2–8°C for short-term, -20°C for long-term.
- Reconstituted solution: Highly fragile; refrigerate at 2–8°C and use within 30 days.
What is the recommended reconstitution procedure?
- Solvent: Bacteriostatic Water (preferred for multi-dose) or Sterile 0.9% Saline.
- Standard Dilution: Add 3mL solvent to a 5000iu vial → 1650iu/mL concentration.
- Handling: Drizzle solvent down vial side. Gently roll/swirl until clear. Do not shake—glycoprotein is sensitive to mechanical stress.
Compliance Notice
For research use only. Not for human consumption.
This product is intended strictly for laboratory research purposes.
For topical application only.
Not for human or animal consumption, injection, or therapeutic use.
