For research use only. Not for human consumption.
CJC-1295 (No DAC)
For topical application only.
CJC-1295 (No DAC) is a synthetic tetrasubstituted 29-amino acid peptide analog of Growth Hormone Releasing Hormone (GHRH). It is primarily studied for its receptor affinity, pulsatile secretion patterns, and effects on cellular signaling pathways related to growth hormone regulation.
Technical Specifications
| Feature | Details |
|---|---|
| Purity | 99% (Validated by HPLC) |
| Concentration | 10mg per vial |
| Molecular Formula | C₁₅₂H₂₅₂N₄₄O₄₂ |
| Molecular Weight | ~3367.97 g/mol |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ |
| Physical Form | White lyophilized powder |
Key Product Features
- Receptor Affinity: Investigated for binding to GHRH receptors in the anterior pituitary.
- COA Verified: Each batch undergoes HPLC and Mass Spectrometry testing to ensure 99% purity.
- Short Half-Life: The “No DAC” version has an approximate 30-minute half-life, suitable for in vitro studies requiring controlled receptor stimulation.
Research Mechanisms
- Somatotroph Stimulation: Studied for receptor-mediated activation of GH synthesis and secretion pathways.
- Signaling Pathways: Used in research examining IGF-1 related intracellular signaling and protein synthesis regulation.
- Metabolic Studies: Investigated in models exploring lipid metabolism and cellular bioenergetics.
Research FAQ
Difference Between DAC and No DAC:
- No DAC (Mod GRF 1-29): Short half-life (~30 minutes), suitable for pulsatile receptor activation studies.
- With DAC: Contains a Drug Affinity Complex for extended half-life; produces continuous receptor occupancy and prolonged signaling in research models.
Storage Instructions:
- Lyophilized powder: 2–8°C for short-term use; -20°C for long-term preservation (up to 2 years).
- Reconstituted solution: Refrigerate and use within 21 days.
Reconstitution Procedure:
- Solvent: Bacteriostatic Water or Sterile Water for Injection.
- Dilution: 10mg vial + 2mL solvent → 5mg/mL solution.
- Handling: Slowly tilt and roll the vial to dissolve; avoid shaking or vortexing.
Research Applications:
CJC-1295 is often used alongside GHRP analogs in receptor signaling studies to examine synergistic effects on growth hormone pathways.
Compliance Notice
For research use only. Not for human consumption.
This product is intended strictly for laboratory research purposes.
For topical application only.
Not for human or animal consumption, injection, or therapeutic use.
For research use only. Not for human consumption.
