For research use only. Not for human consumption.
MOTS-c
For topical application only.
MOTS-c is a 16-amino acid mitochondrial-derived peptide (MDP) primarily studied for its role in mitochondrial-to-nuclear signaling and the regulation of cellular energy homeostasis. In laboratory research, it is used to investigate metabolic pathways, gene expression modulation, and cellular responses to metabolic stress.
Technical Specifications
| Feature | Details |
|---|---|
| Purity | 99% (Validated by HPLC) |
| Concentration | 10mg per vial |
| Molecular Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ |
| Molecular Weight | ~2174.62 g/mol |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Physical Form | White lyophilized powder |
Key Product Features
- Mitochondrial Signaling: Studied as a mitokine facilitating communication between mitochondria and the nucleus for metabolic regulation.
- Research-Grade Purity: Verified via HPLC and Mass Spectrometry to ensure ≥99% purity for reproducible laboratory studies.
- Stable Lyophilization: Vacuum-sealed to maintain peptide integrity during storage and transport.
- Laboratory Use Focused: Designed strictly for analytical, biochemical, and in vitro research applications.
Mechanism of Action (Research Context)
MOTS-c is investigated for its effects on metabolic and cellular pathways in controlled research environments:
- AMPK Pathway Modulation: Studied for activating AMP-activated protein kinase to enhance glucose uptake and mimic aspects of exercise-induced metabolism.
- Lipid Metabolism Research: Used in studies exploring fatty acid oxidation and adipose tissue regulation in in vitro and cellular models.
- Cellular Aging & Longevity: Applied in research on metabolic flexibility, aging processes, and mitochondrial function under stress conditions.
Research FAQ
How should MOTS-c be stored?
- Lyophilized Powder: Store at 2–8°C for short-term use or at -20°C for long-term preservation (up to 24 months).
- Reconstituted Solution: Keep refrigerated at 2–8°C and use within 7–10 days under controlled laboratory conditions.
What is the recommended reconstitution procedure?
- Solvent: Bacteriostatic Water or Sterile 0.9% Saline
- Standard Dilution (for laboratory preparation):
- Add 2mL solvent to a 10mg vial for 5mg/mL
- Add 1mL solvent to a 10mg vial for 10mg/mL
- Handling: Allow vial to reach room temperature before adding solvent. Slowly add solvent along the vial wall and gently swirl until dissolved. Do not shake to prevent peptide aggregation.
Why is MOTS-c called an “Exercise Mimetic”?
In research models, MOTS-c activates metabolic pathways similar to those triggered by endurance exercise, making it a key subject in studies of energy regulation, obesity, type 2 diabetes, and age-related metabolic decline.
Compliance Notice
For research use only. Not for human consumption.
This product is intended strictly for laboratory research purposes.
For topical application only.
Not for human or animal consumption, injection, or ingestion.
