For research use only. Not for human consumption.
PT-141 (Bremelanotide)
For topical application only.
PT-141 is a synthetic, cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). Structurally related to Melanotan II, PT-141 is used in laboratory research to investigate melanocortin receptor signaling and central nervous system (CNS) receptor interactions under controlled experimental conditions.
Technical Specifications
| Feature | Details |
|---|---|
| Purity | 99% (Validated by HPLC) |
| Concentration | 10mg per vial |
| Molecular Formula | C₅₀H₆₈N₁₄O₁₀ |
| Molecular Weight | ~1025.16 g/mol |
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| Physical Form | White lyophilized powder |
Key Product Features
- Research-Grade Purity: Each batch is verified via HPLC and Mass Spectrometry to ensure 99% purity for reproducible laboratory data.
- Cyclic Peptide Stability: Lyophilized and vacuum-sealed to maintain the integrity of the cyclic structure under experimental conditions.
- Laboratory Use Focused: Designed strictly for in vitro and analytical research on receptor binding, signaling pathways, and CNS activity.
Mechanism of Action (Research Context)
PT-141 is studied in laboratory research for its interaction with melanocortin receptors:
- Melanocortin Receptor Interaction: Applied in experiments examining binding dynamics to MC3R and MC4R receptors in CNS models.
- Neurochemical Signaling: Used in research investigating peptide-induced modulation of dopamine and other neurotransmitter pathways in neuronal assays.
- Central Nervous System Studies: Utilized in controlled models for mapping receptor-mediated signaling and neural pathway responses.
Research FAQ
What are the storage and stability requirements?
- Lyophilized Powder: Store at 2–8°C for short-term use or at -20°C for long-term preservation.
- Reconstituted Solution: Keep refrigerated at 2–8°C and use within 21 days under controlled laboratory conditions.
What is the recommended reconstitution procedure?
- Solvent: Bacteriostatic Water or Sterile 0.9% Saline
- Standard Dilution (for laboratory preparation):
- Add 2mL of solvent for a 10mg vial to achieve 5mg/mL
- Add 1mL of solvent for a 10mg/mL solution
- Handling: Slowly add solvent along the vial wall and gently swirl until dissolved. Do not shake to preserve cyclic peptide structure.
Compliance Notice
For research use only. Not for human consumption.
This product is intended strictly for laboratory research purposes.
For topical application only.
Not for human or animal consumption, injection, or ingestion.
